IllustrationAS I WAS DRIVING DOWN THE HIGHWAY I PRESSED ON GAS PEDAL AND VEHICLE MADE A VERY LOUD CHAIN WHINE NOISE AND IT CUT OFF IN THE MIDDLE OF HIGHWAY AND NEVER STARTED BACK UP.
2006 MERCEDES-BENZ R350
Owner reports · Recalls · Investigations
Limited comparison data
There is not enough comparable history to draw a useful model-year comparison.
About this comparison →How this year compares
Owner complaints by model year
Compare all R350 years →Counts vary with age, sales and reporting. They are not failure rates.
What owners reported most
All reported categories
Tap a category to read its complaints. One report may name several components.
When problems were reported
Mileage at the reported incident
30–25K
1525–50K
2350–75K
2775–100K
18100–150K
3150K+
89 reports with mileage · 10 unknown
NHTSA’s mileage field refers to the reported incident, not necessarily the filing date. This shows report counts, not the likelihood of a failure.
What to inspect
Issues worth paying extra attention to based on owner reports.
- Suspension. Review the 26 owner reports in this category and discuss these concerns during a pre-purchase inspection. Read reports →
- Engine. Review the 17 owner reports in this category and discuss these concerns during a pre-purchase inspection. Read reports →
- Engine And Engine Cooling. Review the 16 owner reports in this category and discuss these concerns during a pre-purchase inspection. Read reports →
NHTSA owner reports · September 18, 2026 snapshot.
2 crash reports10 fire reports3 injury reports
Unknown Or Other complaints
4 reportsI DON'T KNOW. *TR
2006 MERCEDES BENZ R 350, CHECK ENGINE LIGHT ILLUMINATED UNDER NORMAL DRIVING CONDITIONS AT APPROX 66,000 MILES; POSSIBLE BALANCE SHAFT WEAR INDICATIONS; MB DEALER CLEARED CEL AND PERFORMED TEST DRIVE WITHOUT IT REAPPEARING; CEL ILLUMINATED AGAIN WITHIN 50 MILES; SUBSEQUENT VISIT TO MB DEALER CONFIRMED EARLY WEAR ON BALANCE SHAF…
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2006 MERCEDES BENZ R 350, CHECK ENGINE LIGHT ILLUMINATED UNDER NORMAL DRIVING CONDITIONS AT APPROX 66,000 MILES; POSSIBLE BALANCE SHAFT WEAR INDICATIONS; MB DEALER CLEARED CEL AND PERFORMED TEST DRIVE WITHOUT IT REAPPEARING; CEL ILLUMINATED AGAIN WITHIN 50 MILES; SUBSEQUENT VISIT TO MB DEALER CONFIRMED EARLY WEAR ON BALANCE SHAFT GEAR AND TIMING CHAIN; MERCEDES BENZ KNOWS THAT THE MATERIALS USED WERE INSUFFICIENTLY HARDENED, CAUSING PREMATURE WEAR AND POSSIBLE SUDDEN LOSS OF POWER RESULTING IN NO POWER STEERING OR POWER BRAKES WITHOUT WARNING , THEREBY PRESENTING A DANGER TO VEHICLE OCCUPANTS; SAFETY RECALL IS IN ORDER FOR VEHICLE OWNERS WITH SIMILAR ENGINE TYPES
2006 MERCEDES BENZ R350 PROBLEM WITH FAULTY TRANSMISSION **CC THE VEHICLE ROLLED BACKWARDS OUT OF THE DRIVEWAY AND STRUCK A PARKED CAR. THE CONSUMER WAS TOLD BY THE DEALER, THE REASON WHY THE VEHICLE ROLLED, WAS BECAUSE HE LEFT THE KEYS IN THE IGNITION. THE CONSUMER STATED A BUTTON MUST BE PUSHED TO PLACE IN TO PARK. IT WAS DET…
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2006 MERCEDES BENZ R350 PROBLEM WITH FAULTY TRANSMISSION **CC THE VEHICLE ROLLED BACKWARDS OUT OF THE DRIVEWAY AND STRUCK A PARKED CAR. THE CONSUMER WAS TOLD BY THE DEALER, THE REASON WHY THE VEHICLE ROLLED, WAS BECAUSE HE LEFT THE KEYS IN THE IGNITION. THE CONSUMER STATED A BUTTON MUST BE PUSHED TO PLACE IN TO PARK. IT WAS DETERMINED THAT THE CONSUMER DIDN'T PLACE THE VEHICLE INTO PARK. IT WAS STATED THAT IF THE KEY IS LEFT IN THE IGNITION, AND NOT PLACED INTO PARK, THE VEHICLE WILL NOT GO INTO PARK BY ITSELF. THE CONCLUSION WAS USER ERROR. THE CONSUMER BELIEVED THERE IS A MANUFACTURER'S DEFECT WITH THE TRANSMISSION. THE CONSUMER DID NOT HAVE A POLICE REPORT. *JB
Official recalls
224V298000 · Service Brakes, Hydraulic:power Assist:vacuum
Apr 26, 2024
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML, GL, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.
Consequence & remedy
Consequence: Reduced brake performance or brake failure can increase the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster. All repairs will be performed free of charge. Owner notification letters were mailed on May 24, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MMUSA's number for this recall is 2024050001/2. This recall is an expansion of previous recall number 22V-315.
22V315000 · Service Brakes, Hydraulic:power Assist:vacuum
May 9, 2022
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML-Class, GL-Class, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.
Consequence & remedy
Consequence: Reduced brake performance or brake failure can increase the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster. All repairs will be performed free of charge. Owner notification letters were mailed June 30, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers for this recall are 2022050014, 2022050015 2022090006, & 2022090007.
Model-level recall history does not show whether a particular VIN is affected or has received a repair. Check a VIN with NHTSA ↗
NHTSA investigations
0No exact-year investigations in this snapshot.